Other symptoms of osteochondral defect knee pain include: Swelling and inflammation; Warmth and redness over the area of the knee joint; Increased body temperature or fever as a result of the body’s attempt to fight infection of the area. Osteochondral fracture of the lateral femoral condyle is a rare injury of the knee joint, which mostly occurs in adolescence 1.In adolescence, the cartilage‐bone interface is the weakest transitional area in the knee joint, and there is no obvious boundary between calcified and uncalcified cartilage 2.The biomechanical strength of immature osteochondral junction was lower … A common type of knee injury is damage to the articular cartilage, the smooth substance that covers the ends of the bones and keeps them from rubbing together as you move. Many of the worst ligament and cartilage injuries in professional sports are considered severe osteochondral defects. It can cause symptoms either after an injury to a joint or after several months of activity, especially high-impact activity such as jumping and running, that affects the joint. It occurs when a small segment of bone begins to crack and separate from its surrounding region due to a lack of blood supply. Most osteochondral defects are caused by one of two events: Wear and tear over time; Injury from sports or physical activity: Injuries usually occur with a combination of twisting force and direct impact that damages the cartilage. Osteochondritis dissecans (OCD) is a condition that develops in joints, most often in children and adolescents. Keywords: Knee, Cartilage, Synovitis, Pigmented villonodular Pigmented villonodular synovitis (PVNS) is a rare, benign, but potentially recurrent condition with an estimated incidence of 1.8 per million. The large osteochondral defect was eventually managed in a staged manner with bone grafting and osteochondral autograft transfer. An Osteochondral lesion is an injury to the articular cartilage and the bone beneath it. In the management of large cartilage defects, the two classically utilized cartilage restoration procedures are osteochondral allograft (OCA) transplantation and cell therapy, or autologous chondrocyte implantation (ACI). Osteochondritis dissecans is an idiopathic disease which affects the subchondral bone and its overlying articular cartilage due to loss of blood flow. [2] That process can lead to pain, loose body formation and joint effusion.[1]  [1] This may result in separation and instability of a segment of cartilage and free movement of these osteochondral fragments within the joint space. Causes and Basic Symptoms. Osteochondritis dissecans occurs most often in children and adolescents. Prevalance and Outcome of Treatment. Although understanding of these conditions has evolved substantially with the use of high-spatial-resolu … Infection is always a … Patient- and lesion-specific factors must be identified when evaluating a patient with an articular cartilage defect. - Articular cartilage defects: study of 25,124 knee arthroscopies - Articular cartilage lesions in 993 consecutive knee arthroscopies - Exam: - symptoms of intermittent locking, recurrent effusions, crepitus, and persistant pain may all be associated with chondral injuries; See: - Knee Joint Menu: - Arthroscopy of the Degenerative Knee - Osteochondritis Dessicans - Osteoarthritis - Discussion: - described types articular cartilage lesions; - mild lesion, w/ normal appearing cartilage - it is difficult to dissern borders of lesion and normal surrounding cartilage. It usually occurs in the knee, ankle or elbow. Several pathologic conditions may manifest as an osteochondral lesion of the knee that consists of a localized abnormality involving subchondral marrow, subchondral bone, and articular cartilage. Treatment of Chondral (Cartilage) Lesions. Injuries can range from a fine crack of the joint surface all the way though to a piece of the bone breaking away. Osteochondral injuries are … The condition occurs most commonly in the knee, but also occurs in elbows, ankles and other joints. Introduction. A Study of 5233 Knee Arthroscopies.